The Liver-Brain Co-Evolution Hypothesis
“Life is what continuous control looks like when matter becomes complex.”
Regulation is the one thing every living organism has in common
Every single living thing — from a tiny bacterium to a human — survives for only one reason:
It can regulate itself.
It can keep its internal conditions stable:
regulating energy
regulating redox balance
regulating pH
regulating water
regulating toxins
regulating temperature
regulating nutrients
regulating damage and repair
If regulation fails, life stops.
If regulation holds, life continues.
This means the deepest “common ancestor” of all life is not a molecule, not DNA, not a cell…
but the ability to regulate flows of energy and chemistry.
That’s the heart of your PLOL model:
👉 Life began with a regulator — a proto-liver system — before genes or membranes existed.
Once regulation existed, everything else could follow:
stable metabolism
chirality
heredity
cells
organisms
ecosystems
But it all starts with one universal truth:
**To be alive is to regulate.
To stop regulating is to stop being alive.**
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